Daya Antibakteri Ektrak dan Fraksi Daun Ubi Rambat (Ipomea batatas L) Terhadap Pertumbuhan bakteri Pseudomonas aeruginosa

ABSTRACT: Polyphenols are compounds that contained in some of the plants and fruits play a role in health protection by improving immune system, reducing risk of cancer and neurodegenerative diseases. This polyphenol compounds serve as antioxidants for free radical scavenging, and antibacterial with disrupting permeability of cell membrane. The rich of polyphenols in sweet potato leaves (Ipomea batatas L.) can be utilized to inhibit the growth of Pseudomonas aeruginosa. Sweet potato leaves are extracted by maceration methods. The solvent used is ethanol. This research aims to determine antibacterial activity of extracts, n-hexane, ethyl acetate and n-butanol fractions of Sweet Potato (Ipomea batatas L) leaves against Pseudomonas aeruginosa. The antibacterial activity determined by disc diffusion and macrodilution methods. The concentrations of extract are 62.5 μg/125 μg/mL, mL, 250 μg/mL, 500 μg/mL, 1000 μg/mL . n-butanol fraction has the highest antibacterial activity than others with average diameter of inhibition zone 12.63 mm. Macrodilution test show MIC values of extracts and fraction is 500 μg/mL.
Keyword: Sweet potato leaves, antibacterial, diffusion method, macrodilution method
Penulis: Desi Sagita, Siti Hamidatul A, Silvi Riska Ilahi
Kode Jurnal: jpfarmasidd170124

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