THE DIFFERENCE IN THE TOTAL CHOLESTEROL/HDL-C RATIO IN TYPE-2 DM PATIENTS WITH DIABETIC ULCERS AND WITHOUT DIABETIC ULCERS IN BETHESDA HOSPITAL YOGYAKARTA
Abstract: Diabetes mellitus
(DM) is one of the diseases that annually shows an increase. An increase of DM
prevalence will follow the increasing diabetic ulcers complication. Cholesterol
could influence to create ulcer through atherosclerosis process. Ratio of total
cholesterol/HDL is an important predictor to detect early risk of vascular
complication in type 2 DM patients that can manifest as diabetic ulcers. This
study aims to know whether there is any difference in the Total
Cholesterol/HDL-C Ratio in type-2 DM patients with diabetic ulcers and without
diabetic ulcers. This study was an analytic observational with cross-sectional
approach. Data collection was done using the purposive sampling with a sample
size of 30 patients of diabetes mellitus with diabetic ulcers and 30 patients
without diabetic ulcers. The data were analyzed by Mann-Whitney. The median
results in Total cholesterol/HDL-C ratio between Type-2 DM patients with
diabetic ulcers and without diabetic ulcers were 6.025 and 3.680 respectively.
The median of cholesterol total/HDL-C ratio Type-2 DM patients with diabetic
ulcers was higher than those without diabetic ulcers. Mann-Whitney showed the
value of P = 0.000, so that this study
found a significant difference. In conclusion, the ratio of total
cholesterol/HDL-C in type-2 DM patients with diabetic ulcer was significantly
higher than type-2 DM patients without diabetic ulcers in Bethesda Hospital,
Yogyakarta.
Keywords: diabetic ulcers;
HDL; total cholesterol; type-2 diabetes mellitus
Penulis: Devina Sagitania,
Purwoadi Sujatno, Fenty Fenty
Kode Jurnal: jpfarmasidd180153
