Pengaruh Pemberian Fraksi Ekstrak Etanol Kelopak Bunga Rosella (Hibiscus sabdariffa L.) Terhadap Volume Urin Tikus Putih Jantan
Abstrak: Research on the
effect of giving the fraction of ethanolic extracts of roselle calyx (Hibiscus sabdariffa L.) to male white rats
urine volume has been done, the fraction
was given orally at a dose of n-hexane fraction of 95 mg/g BW, the fraction of
ethyl acetate 145 mg/g BW and the fraction of the remaining 350 mg/g BW once a
days for 7, 14 and 21. Result shows that the fraction of n-hexane giving 95
mg/g BW, fraction ethyl acetate of 145
mg/g BW, and the remaining fraction of 3450 mg/kg BW roselle calyx (Hibiscus sabdariffa L.) can effect urine
volume increased male white rats. Duration of the three fractions on days 7, 14
and 21 show a not significant increase in urine volume (P<0.05).
Kata Kunci: Diuretic, Hibiscus
sabdariffa L., fraction of ethanol extract
Penulis: Surya Dharma, Desis
Rena, Zet Rizal
Kode Jurnal: jpfarmasidd130389
