Pengaruh pemberian yogurt sinbiotik tepung pisang tanduk terhadap profil lipid tikus sindrom metabolik
Abstract: The metabolic
syndrome, which is characterized by hyperglycemia, obesity, dyslipidemia,
hypertension, prothrombic and proinflamatory state, is a risk factor for
cardiovascular disease and diabetes mellitus. The synbiotic yogurt of tanduk
banana (Musa paradisiaca fa. corniculata) flour contains lactic acid bacteria,
fructooligosaccarides, flavonoids, and vitamin C which all of them play role in
improving the lipid profile.
Objective: The aim of this study was to prove the effect of synbiotic
yogurt of tanduk banana flour on lipid profile of metabolic syndrome rats.
Method: This study was an true experimental with pre-post test control group design. The subject of this
study were 18 metabolic syndrome male Wistar rats divided into 3 groups,i.e
control group (standart diet), intervention group I (standart diet and synbiotic
yogurt of banana flour 0,009 ml/g weight/day), and intervention group II
(standart diet and synbiotic yogurt of banana flour 0,018 ml/g weight/day). The
intervention period was 2 weeks. Different test before and after intervention
used paired t-test. The difference test between groups used One-Way ANOVA and
Kruskal wallis.
Results: The result showed that both of intervention group improved lipid
profile significantly (p<0,05). The intervention group II showed more
effective improvement of lipid profile significantly (p<0,05) than intervention
group I. The intervention group II decreased triglycerides level 41,56%; total
cholesterol level 41,39%; LDL-cholesterol level 57,5%; and increased
HDL-cholesterol level 139,62%.
Conclucion: The intervention of synbiotic yogurt of tanduk banana flour can decrease triglyceride
level, total cholesterol level, LDL-cholesterol level, and increase
HDL-cholesterol level.
Keywords: lipid profile;
metabolic syndrome; synbiotic; wistar rats; yogurt
Penulis: Zana Fitriana Octavia
Kode Jurnal: jpkesmasdd170528
