Pengaruh yogurt sinbiotik pisang terhadap kadar glukosa dan insulin tikus sindrom metabolik
Abstract: The metabolic
syndrome often begins with insulin resistance characterized by hyperinsulinemia
and hyperglycemia. Synbiotic yoghurt tanduk banana contains probiotic and
prebiotic FOS can improve insulin resistance in metabolic syndrome.
Objective: To prove the effect of synbiotic yoghurt tanduk banana can
reduce blood glucose levels and insulin levels in metabolic syndrome rats.
Method: True-experimental study with randomized controlled group pre-post
test design in male wistar rats. Eighteen samples were induced to become
metabolic syndrome with high fat fructose diet for 2 weeks and they were
divided into 3 groups: control (K) was given standard diet, treatment group 1
(P1), and treatment group 2 (P2) were given sinbiotic yoghurt tanduk banana
dose of 0.009 ml/g body weight (BW)/day and 0.018 ml/g BW/day for 2 weeks.
Results: The paired t-test showed there were differences of blood glucose
levels and insulin levels before and after treatment in P2 group. The Kruskal
Wallis test showed there were differences of mean blood glucose levels inter
group after treatment (p<0.05). The One-way Anova test showed there were
differences of mean insulin levels inter group after treatment (p<0.05).
Conclusion: Synbiotic yoghurt tanduk banana can reduce blood glucose
levels and insulin levels in metabolic syndrome rat with effective dose is
0.018 ml/grBW/day.
Keywords: blood glucose;
insulin; metabolic syndrome; synbiotic yoghurt banana
Penulis: Fiqhi Cahyaningrum
Rahmawati
Kode Jurnal: jpkesmasdd170529
