Antioxidant Activity of Prenylated Flavonoid Compound from Dichloromethane Extract of Artocarpus communis Leaves
Abstract: This research
investigated the antioxidant activity of prenylated flavonoid compound from the
ichloromethane extract of Artocarpus communis leaves on 1,1-diphenyl-2-picryl
hydrazyl freeradicals scavenging assay. The dichoromethane extract of
Artocarpus communis leaves was fractionatedby column chromatography techniques
on silica gel, and each fraction was assayed for its activity. The active
compound,
1-(2,4-dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1- benzopyran-5-yl]
1-propanone, showed moderate antioxidant activity with IC50 54.6 µg mL-1.
Keywords: Artocarpus communis,
prenylated flavonoid, antioxidant activity
Penulis: PUSPA D.N. LOTULUNG,
SOFA FAJRIAH, EUIS FILAILA
Kode Jurnal: jpfarmasidd110185
