Efek Daun Alpukat (Persea Americana M.) dan Daun Kelor (Moringa Oleifera L.) terhadap Peningkatan Kadar HDL Pada Model Tikus Putih Hiperlipidemia
Abstract: Hyperlipidemia is a
lipid metabolism disorder which is characterized by decreasing of High Density
Lipoprotein (HDL) level. Avocado (Persea americana) and Kelor (Moringa
oleifera) leaves can be proposed for increasing HDL level. This research aimed
to determine the steeping combination of avocado and kelor leaves effect to
against HDL level for hyperlipidemia rat model. This research used true
experimental pre and post test with control design. Amount of 36 rats were
divided into negative control (A), single dose of Persea leaves steeping
36mg/200gramBB (B), combination of 36mg/200gramBW Persea leaves and 54
mg/200gramBW Moringa leaves (C), combination of 18mg/200gramBB Persea leaves
and 27 mg/200gramBW Moringa leaves (D), single dose of Moringa leaves steeping
54mg/200gramBW (E), and simvastatin 0,018 mg/day (F). Data were analyzed by
ANOVA test and continued by Duncan
post-hoc test. ANOVA tests showed there are significant differences bethween
group (p = 0.008). Duncan post hoc test showed that the combination group and
simvastatin control group are equally strong to increase HDL levels. The
steeping combination of Persea and Moringa leaves has an effect to increasing
HDL level.
Keywords: Persea americana
leaf; Moringa leaf; simvastatin; HDL; Daun alpukat; Daun kelor
Penulis: Sri Handayani,
Saryono, Hernayanti
Kode Jurnal: jpkeperawatandd170252
