Asupan zink dan magnesium makanan dengan disfungsi ereksi pada penderita sindrom metabolik
Abstract: Metabolic syndrome
(MetS) is a disease of disorder of lipid and nonlipid metabolism. The West of
Scotland Coronary Prevention Study found that men with MetS had probability 3.7
dysfunctions of erection (ED) by using International Index of Erectile Function
(IIEF). Patient with heart disease had the risk 2 times to get ED, hypertension
was 1.5-2 times, DM was 3-4 times, depression was 2-3.5 times, testosterone
deficiency syndrome (TDS) was 1.5-2 times, and high cholesterol was 4 times.
The nutrient deficiency of zinc (Zn) and magnesium (Mg) was suspected being the
main component which had a role in resisting a sexuality growth and maturation
process.
Objective: Knowing the correlation of Zn and Mg feeding with erection
dysfunction in MetS person.
Method: This study was observational analytic study, with case-control
design in the patient aged 30-60 years old. The respondent in this study was
people with MetS according to WHO criterion. There was 82 patient divided into
two groups, consist of 41 cases of MetS and ED, 41 cases with the normal
patient. The data collected by interview, laboratory assessment and
anthropometric measurement. The data analysis using univariate, bivariate and
multivariate analysis using multiple logistic regression.
Results: There was significant correlation between Zn feeding and ED
(OR=7.15; 95% Cl=1.47-34.71; p=0.007) and there was significant correlation
between Mg feeding with ED (OR=3.34; 95% Cl=1.07-10.4; p=0.033). The end result
of the multivariate analysis showed the risk variable to the ED event, that was
Zn feeding with OR=15.41. If the intake of Zn accompanied with risk factors
associated as a cause of ED, multivariate analysis showed HbA1c’s degree with
OR=12.57; triglyceride (OR=10.47); blood pressure (OR=5.82); and abdominal
obesity (OR=6.94). The result shows that these risk factors can aggravate or
anticipate the onset of dysfunction erection beside low Zn intake.
Conclusion: There was statistically significant correlation between Zn and
Mg feeding with erection dysfunction in MetS patient.
Keywords: metabolic syndrome;
erection dysfunction; zinc and magnesium
Penulis: Saraheni Saraheni
Kode Jurnal: jpkesmasdd140733
