ULTRASTRUCTURAL FEATURE OF KOI HERPESVIRUS (KHV) INFECTED CULTURED KOI FIN (KF-1) CELLS
Abstract: Koi herpesvirus
(KHV), may cause significant morbidity and mortality in common carp (Cyprinus
carpio). In the present study, an electron microscopic (EM) was performed on
KHV-infected cultured koi fin (KF-1) to document the ultrastructure of the
lesions. Viral particles were firstly evident in the nucleus. These viral
particles observed as immature capsids and nucleocapsids. Many non-enveloped
nucleocapsids have moved from the nucleus into the cell cytoplasm. The formation
of subviral particles and virions, which comprised, in turn, an electron dense
core, capsids with a hexagonal outline, the tegument was evident in the
cytoplasm. And then, the virions with the enveloped tegument budded through the
intracytoplasmic membrane. Based on EM results, the definitive pathological
change was similar as those in the Family Herpesviridae.
Keywords: KHV; KF-1;
nucleocapsid; virion; Herpesviridae
Author: Ketut Mahardika,
Masahiro Yasuda
Journal Code: jpperikanangg110020
