UJI BIOAKTIVITAS EKSTRAK AKAR TABAR KEDAYAN (Aristaolochia foveolata Merr)
Abstrak: East Kalimantan has
very much plant diversity of the various ethnic Dayak. One is a plant Tabar
Kedayan (Aristolochia foveolata Merr) contained in Malinau district,
empirically efficacious as antidiarrheal, antidote (anti-venom), bidder alcohol
for drinkers, to the efficacy of this type of p lant Aristolochia foveolata
Merr not scientifically confirmed, this is because scientific research is still
at least as well as the information contained bioactive compounds in the roots
of Aristolochia foveolata Merr which has not been published and similarly with
bio logical act ivity is not widely studied. This study aims to determine the
chemical constituents of plants Tabar kedayan phytochemical screening form,
which includes the bioactivity test toxicity test method Lethaly Brine Shrimp
Test, antibacterial act ivity and antio xidant activity. The results of
research on phytochemical screening of chemical co mpounds are alkaloids,
tannins and flavonoids. Bioactivity test results on the toxicity test method
BSLT 0,5,10,25 and 50 pp m concentration with the percentage of death is
0,40,60,80 and 100% level of to xicity of the ethanol extract of the roots of
Tabar kedayan 7.269 ppm LC50 values obtained and included in tinggat highly
toxic toxicity is 0-250 ug / ml, to test antibakter in Escherichia co li
concentration of 5%, 10%, 20%, and 30% inhibition zones formed with an average
diameter is 4.45 mm, 6.56 mm, 7.86 mm and 8.01 mm, whereas the bacterium
Staphylococcus aureus is in order, with a concentration of 5%, 10%, 20% and 30%
inhibition zones formed with an ave rage d iameter is 4.49 mm, 5.83 mm, 6.61 mm
and 7.55 mm. Test results obtained antio xidant yellow spots after being
sprayed DPPH can be concluded that the ethanol extract has antio xidant power.
Kata Kunci: Tabar Kedayan root
(Aristolochia fofelata Merr), phytochemical screening, toxicity,antibacterial,
antio xidant
Penulis: Siti Jubaidah, Anita
Apriliana, Heri Wijaya
Kode Jurnal: jpkimiadd140695
