UJI EFEK SITOTOKSIK EKSTRAK ETANOL KULIT BUAH ASAM KANDIS (Garcinia cowa Roxb.) TERHADAP SEL KANKER PAYUDARA T47D DENGAN METODA MTT (MICROTETRAZOLIUM) ASSAY
ABSTRACT: The evaluation
of cytotoxic effect
on ethanolic extract
from the fruit
rinds of asam kandis
(Garcinia cowa Roxb.)
on T47D human
breast cancer cells
in vitro had
been evaluated. The cytotoxic effect was carried out by using MTT assay.
Extraction of dried fruit rinds of G.
cowa Roxb. was
macerated with ethanol 70%. The
extract was prepared into 4 concentration
groups, 100, 10,
1, and 0,1
µg/ml. Results showed
that the IC50
of G. cowa Roxb. ethanolic extract was 19,33 µg/ml
± 1,15 on breast cancer T47D cells. The percentage of cells
viability and concentration
were analyzed analyzed
by the two-way
analysis of variance (ANOVA)
followed by Duncan test. Result showed that
the ethanolic extract of G. cowa
Roxb gave a significant effect on T47D breast cancer cells viability
(P<0.05).
Penulis: Fatma Sri Wahyuni,
Suci Sutma, Yufri Aldi
Kode Jurnal: jpfarmasidd110099
