UJI AKTIVITAS SITOTOKSIK EKSTRAK DAN FRAKSI DARI SPON LAUT Petrosia sp DENGAN METODA BRINE SHRIMP LETHALITY TEST
ABSTRACT: Determination of
cytotoxic activity of the extract and fraction of marine sponge Petrosia sp
suing Brine Shrimp Lethality
Test has been done.
The Cytotoxic activity
analysis was done
toward methanol extract first,
then continued to
n-hexane, ethyl acetate
and buthanol fractionsrespectively. The
LC50 values were
70.736 ppm, 269.153
ppm, 197.38 ppm
and 70.667 ppmespectively. Results showed that
the extract and fraction of
Petrosia sp potentially has cytotoxic activity
whereas buthanol fraction has the higest citotoxic activity among at
all. Phytochemistry screening for
buthanol fraction contained terpenoid, steroid and saponin.
Penulis: Krisyanella, Dian
Handayani, Lendra Yunance
Kode Jurnal: jpfarmasidd110092
