Aktivitas Antimalaria Fraksi Etil Asetat Daun Johar (Cassia siamea Lamk) Terhadap Pertumbuhan Plasmodium Falciparum Strain G2300 (Resisten Klorokuin) In Vitro
Abstrak: The aimed
of this study
was to determinate
antimalarial activity of
ethyl acetate fraction
of Johar leaves (Cassia siamea
Lamk). In vitro test of the ethyl acetate fraction performed using G2300 strain
of Plasmodium falciparum (chloroquine-resistant) which has been synchronized
and incubated for 48 hours. The concentration of the test solution of ethyl
acetate fraction were used at 100 ug / ml, 10 ug / ml, 1 ug / ml, 0.1 mg / ml,
0.01 ug / ml. The results showed that the ethyl acetate fraction of C. siamea
Lamk leaves have antimalarial activity against P. falciparum G 2300 strains
chloroquine resistance with IC50 values was
4.46 ug/ml.
Penulis: Wiwied Ekasari, Indah
ST, Tutik Sri W, Aty W, Afraz
Kode Jurnal: jppertaniandd140082
