SINDROMA REYE: dari Etiologi hingga Penatalaksanaan
Abstract: Reye’s syndrome is a
disease that is correlated with acute non-inflamatory encephalopathy and hepatic failure.
Although its cause
is not clear,
this syndrome is
often detected after
an acute viral infection such as influenza, varicella,
or gastroenteritis. Moreover, this syndrome is correlated with the use of aspirin
to cure fever.
Reye’s syndrome is
now differentiated into
two groups: (1)
“Classic” Reye’s syndrome or
“idiophatic” or “North
American type”, and
(2) the “Reye-like”
Inherited Metabolic Disorder (IMD).
Clinical manifestation of
this syndrome is
not specified but
it may include
vomitting with or without
dehydration, ensephalopathy, jaundice,
and more than
50% of it
shows hepatomegali. CDC (Center
for Disease Control and prevention) classifies encephalopathy into 6 stadiums.
Death may be caused by cerebral
edema, intracranial highpressure
or myocardial disfunction,
cardiovascular colaps, respiratory
failure, gastrointestinal hemorrhage, and status epilepticus or sepsis.
Key words: Reye Syndrome;
“Classic” Reye’s Syndrome; The “Reye-like” Inherited Metabolic Disorder (IMD);
aspirin
Penulis: Bambang Hernowo Rusli
Kode Jurnal: jpkedokterandd090090
