Pembuatan Film Balutan Primer Untuk Luka Bakar yang Mengandung Kolagen Kulit Ikan Gabus (Channa striata)

ABSTRACT: Collagen from snakehead fish skin (Channa striata) wound dressing is able to maintain the moisture balance around the wound. Known as modern dressing method, collagen wound dressing is able to accelerate fibrinolysis, fasten angiogenesis, decrease the infection risk, quicken the growth factor creation, and active cell generation. Collagen has an important function in wound healing process because collagen has the ability to hemostatis, interaction with thrombocyte, interaction with fibronectine and increase liquid exudation, improve cellular component, increase growth factor and boost fibroplasia process. Collagen film isolated from snakehead fish (Channa striata) 1%, with additional material such as PVA 4%, propilenglikol 5 %, Gliserin 10% and preservatives nipagin and nipasol. All in all, the collagen characterization result is corresponded to the literature,but it needs improvement for how to dry film, because film contains collagen which can’t be dry at temperatures above 40oC, because it will change the collagen to gelatin.
Kata kunci: kolagen; gel; flm; luka bakar
Penulis: Rahmi Nofita R, Elfi Sahlan Ben,  Yanwirasti
Kode Jurnal: jpfarmasidd170149

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