Isolation and Phisicochemical Characterization of Microcristalline Cellulose from Ramie (Boehmeria nivea L. Gaud) Based on Pharmaceutical Grade Quality
Abstrak: Microcrystalline
cellulose is the most used material for medicine, which able to be found in
fibrous plants. Microcrystal celluloses are being used as filler or binder in
dosage formulas in tablets and capsules. This research aimed to produce
microcrystalline cellulose from ramie based on pharmaceutical grade parameters.
Research method include hemp fiber preparation, α-cellulose isolation,
microcrystalline cellulose production, and microcrystalline cellulose
characterization which compare with Avicel® PH 102 . Result shown
microcrystalline cellulose yield is 57.26%. The result of physicochemical
characterization that can comply the specifications of pharmaceutical grade as
a pharmaceutical excipient.
Keywods: Microcrystalline cellulose, Ramie, physicochemical,
pharmaceutical grade
Penulis: Desy Nawangsari, Anis
Yohana Chaerunisaa, Marline Abdassah, Sriwidodo Sriwidodo, Taofik Rusdiana,
Linda Apriyanti
Kode Jurnal: jpfarmasidd180224
