Aktivitas Antidermatofitik Ekstrak Daun Urang-aring (Eclipta alba (L.) Hassk) terhadap Trichophyton mentagrophytes
Abstract: Emergence of drug
resistance in a fungal infection therapy had driven the need for a search of a
new therapeutic agent. Traditional approach is now being marked by most people
to combat this resistance problem. Plants can acts as a source of antimicrobial
agents. Eclipta alba,L. Hassk leaves has been traditionally used to cure skin
illnesses caused by fungal infection. The aim of this study is to analyze the
antidermatophytic activity of Eclipta alba, L. Hassk leaves extract against
Trichophyton mentagrophytes. Eclipta alba (L.) Hassk leaves were extracted
gradually with hexane, ethyl acetate, ethanol and water. A serial concentration
0 mg/ml, 12,5 mg/ml, 25 mg/ml, 50 mg/ml and 100 mg/ml of those four fraction
was made subsequently. The antidermatophytic activity was done by gel diffusion
method. Zone of inhibition was measured and analyzed with ANOVA continued with
DMRT (Duncan Multiple Range Test). The antifungal test showed that hexane,
ethyl acetate and ethanolic extract of Eclipta alba, L. Hassk leaves were
effective to inhibit the growth of Trichophyton mentagrophytes but not
significantly different (p≥0,05). Water extract showed no inhibition on
Trichophyton mentagrophytes
Keywords: Eclipta alba;
Antidermatophytic; Trichophyton mentagrophytes
Penulis: Hartanti Dian Ikawati
Kode Jurnal: jpfarmasidd140566
