AKTIVITAS ANTIBAKTERI EKSTRAK AKAR CEPLUKAN (PHYSALIS ANGULATA L.) TERHADAP STAPHYLOCOCCUS EPIDERMIDIS DAN PSEUDOMONAS AERUGINOSA
ABSTRACT: Root ceplukan
(Physalis angulata L.) is one of the medicinal plants that contain several
active compounds that are antibacterial. This study aims to prove the antibacterial
activity of root ceplukan extract againsts Staphylococcus epidermidis bacteria
and Pseudomonas aeruginosa bacteria. Root ceplukan was extracted by maceration
with ethanol 70%. Root root extracts of phytochemical screening include
flavonoids, alkaloids and saponins. The ceplukan root extract was then tested
against S. epidermidis and P. aeruginosa bacteria using wells method with
concentrations of 20%, 40%, 60%, 80%, 100%, aquades as a negative control and
amikacin as a positive control. Inhibitory zone diameter with each
concentration for P. aeruginosa bacteria, among others, negative control = 0
mm, positive control = 21,623 mm, 100% = 16.9 mm, 80% = 15.05 mm, 60% = 13.703
mm, 40% = 12.02 mm, 20% = 12.02 mm and S. epidermidis bacteria have inhibitory
zone at positive control of 21,623 mm. The results of this study showed that
root extract ceplukan proved to have inhibition zone against bacteria P.
aeruginosa at all concentrations but has no inhibition zone against S.
epidermidis bacteria. Root ceplukan extract has a minimum inhibitory
concentration of 14% and a minimum bacterisid concentration of 20%, against P.
aeruginosa bacteria. The results of phytochemical analysis showed that root
ceplukan positively contain flavonoids, alkaloids and saponins are suspected as
antibacterial compounds.
Keywords: Antibacterial,
Staphylococcus epidermidis, Pseudomonas aeruginosa, Ceplukan root extract
Penulis: Pratika Viogenta,
Lilik Koernia Wahidah, Ika Harum Saputri
Kode Jurnal: jpfarmasidd170059
