UJI EFEKTIVITAS SEDIAAN HAND SANITIZER KOMBINASI EKSTRAK DAUN KEMANGI (OCIMUM SANCTUM L) DAN EKSTRAK KULIT JERUK PURUT (Citrus hystrix)
Absctract: Antiseptic
Activity, Kemangi Leaf- Cytrus Hystrix Leather, Gel Antiseptic (Hand
Sanitizer). It is known kemangi leaf had contained saponins, flavonoids and
tannins that benefit as antibacterial, while in research by Susanti, 2010 had
proven that leather of Citrus hystrix contained essential oil as antibacterial
and used as antiseptic in pharmaceutical case. So, to get the optimal formula
as hand sanitizer or antiseptic gels used combination two extracts kemangi leaf
and Citrus hystrix leather. This research is an experimental research with Post
Test Control Group Design to analyze antiseptic activity using the Replica
methods with to account the number of colonies of microorganism. Statistic test
to the number of colonies of microorganism with Anova Test one way that
confidence level 95% and obtained significance 0,000 the result P < 0,05 and
continued to Tukey HSD test that confidence level 95%. The result statistic tes
showed that have significan differences between negative control with the
formula of gel antiseptic combination extract of kemangi leaf and extract
Cytrus hystrix leather, so this formula have activity as antiseptic. The most
effective variation concentration is concentration extract of kemangi leaf 75%
and extract Cytrus hystrix leather 25%.
Keywords: Antiseptic Activity,
Kemangi Leaf- Cytrus Hystrix Leather, Gel Antiseptic (Hand Sanitizer)
Penulis: Indri Kusuma Dewi,
Bambang Yunianto
Kode Jurnal: jpkebidanandd160431
