ANTIMICROBIAL PEPTIDES SEBAGAI OBAT ALTERNATIF PADA RESISTENSI ANTIBIOTIK
ABSTRACT: Antibiotic
resistance has become a global public-health problem, thus it is imperative
that new antibiotics have to be developed continously. Antimicrobial peptides
(AMPs) are component of the innate immune response, which is the principal
defence system for the majority of living organisms. Similar to antibiotics,
most AMPs have a broad antimicrobial spectrum and highly active against fungi.
AMPs are known to have interaction with biomembranes to lyse microbial cells.
Many researches have tried to develop AMPs as future drugs for antibiotic
resistance. Many AMPs also possess antiviral or anti-parasite activity.
However, antimicrobial peptides have their own disadvantages. We review the
role of these molecules in human’s health, their advantagesand disadvantages as
alternative antimicrobial for antibiotic resistance.
KEYWORDS: Antimicrobial
peptides; Antibiotics; Antibiotic resistance
Penulis: Nyoman Fitri
Kode Jurnal: jpfarmasidd120323
