Asupan seng dan status seng yang rendah sebagai faktor risiko kejadian infeksi filariasis (studi kasus di kota pekalongan)
Abstract: Microfilariae
infections in the human body does not always cause symptoms. filaria infected
humans would induce a Th2 response by increasing the production of IL-4, IL-5,
IL-13 and increased serum levels of IgE. Zinc deficiency is directly related to
the regulation of immune response that is reduced due to decline in
lymphopoesis as well as the effect on the immune response and the production of
antibodies in people with normal nutritional status.Objective: This research is
analytic survey with case control approach. Samples were selected with a total
engineering sample of 42 people infected with filariasis of the samples taken
by Comparing the number of 1 : 1. The subjects of the study were obtained when
only 30 cases and 30 controls chosen. Zinc intake assessment is done by using a
food frequency ( FFQ ) and food recall 3 x 24 hours later treated with
Nutrisoft program. Assessment of serum zinc performed with venous blood
sampling as much as 3 cc made 1 time. Statistical analysis was performed with
chi square test.Results: Group infected and not infected with filariasis less
zinc intake was 54.7 % and 45.3 % , zinc status is lacking in both infected and
uninfected group was 50.0 % and 50.0 %. Thus intake of zinc and zinc status
were less does not constitute a risk factor in the study group ( zinc intake :
Value- p = 0.103 ; OR = 7.250 with a value 95 % CI = 0.815 to 64.45 and zinc
status : p - value = 1.000 ; OR = 1,000 with a value 95 % CI = 0.131 to 7.605
).Conclusion: The intake of zinc and low zinc status is not a risk factor
incidence of filariasis infection in areas of research.
Keywords: filariasis; Asupan
Seng; Seng Serum; Imunitas
Penulis: Dewi Nugraheni Restu
Mastuti
Kode Jurnal: jpkesmasdd150752
