Upper Gastrointestinal Endoscopy as Diagnostic Test for Detection of Gastric Malignancy in Sanglah Hospital Denpasar
Abstract: Gastric malignancy
is the third most common cause of cancer-related death in the world. Upper
gastrointestinal (UGI) endoscopy for detection of gastric malignancy has been
used widely in Indonesia. This study aimed to determine the prevalence of
gastric malignancy and diagnostic value of UGI endoscopy in detection of
gastric malignancy in Sanglah Hospital, Denpasar.
Method: A retrospective study on patients undergoing UGI endoscopy in
Endoscopy Unit of Sanglah Hospital Denpasar between January 2012 and December
2014 was conducted. Endoscopical and histological diagnosis were documented.
The diagnostic test of endoscopic diagnosis were conducted by showing its
sensitivity, specificity, positive predictive value, negative predictive value,
and accuracy.
Results: One thousand and sixty eight patients with upper
gastrointestinal symptoms were subjected to endoscopy between January 2012 and
December 2014. Of the 1068 cases, 39 patients were suspected for gastric
malignant lesions on UGI endoscopy. During the study period,
histopathologically-confirmed gastric malignancy was found in 2.72% patients. The
sensitivity, specificity, positive predictive value, negative predictive value,
and accuracy of UGI endoscopic diagnosis for these neoplastic lesions were
100%, 99.04%, 74.36%, 100%, and 99.06%, respectively.
Conclusion: The prevalence of gastric malignancy was higher compared to
western countries. Endoscopy is important as diagnostic tool in patients with
suspicion of gastric malignancy. Greater suspicion in clinical judgment and
carefulness in excluding malignancy through one histopathology negative
findings need to be done to reduce the number of misdiagnoses of gastric
malignancy.
Keywords: prevalence; gastric
malignancy; histopathology; gastric biopsy
Author: Hendra Koncoro, Putu
Prathiwi Primadharsini, Luh Putulin Indrayani, I Dewa Nyoman Wibawa
Journal Code: jpkedokterangg150435
