The Positive Skin Prick Test not Correlate with Disease Severity and Quality of Life in Atopic Dermatitis Patients
ABSTRACT: Atopic dermatitis
(AD) is a skin disease which cause stress to the patients. The chronic process
of AD can cause physical, social, and psychological impairments. The severity
of AD can also be affected by allergen exposures, which in turn will affect the
quality of life of the patient. Skin prick test (SPT) can be used to evaluate
allergen sensitization. Purpose: To evaluate correlation between SPT positivity
to severity and quality of life of AD patients. Methods: The study was an
observational cross-sectional study. Twenty five AD patients were recruited
based on inclusion and exclusioncriteria. Questionnaire was used to measure the
quality of life of patients, and Scoring of Atopic Dermatitis (SCORAD) to measure
the disease severity. Most of participants were women (80%), with median of age
26.84±13.71. Results: Positive SPT was obtained in 68% of patients, most of
them were caused by house dust mites (55.2%). Seventy six percent of patients
experienced mild AD, 12% moderate AD, and also 12% patients experienced severe
AD. Significant correlation was observed between the severity and quality of
life (p=0.001;r=0.617), while the SPT positivity has no correlation with the severity
(p=0.912;r=-0.023) and quality of life (p=0.959;r=0.011). Conclusion: This
study revealed that the severity of the disease has a correlation with quality
of life, but SPT positivity has no significant correlation with severity and
quality of life.
Key words: atopic dermatitis,
skin prick test, quality of life
Penulis: Oki Suwarsa, Erfina
Rohana Sormin, Endang Sutedja, Hartati Purbo Dharmaji
Kode Jurnal: jpkedokterandd170513
