Successful Combination Therapy of Acne Keloidalis Nuchae
ABSTRACT: Acne keloidalis
nuchae (AKN) is a chronic, inflammatory, idiopathic disorder of hair follicle, characterized
by keloidal papules or plaques on the nape and occipital scalp. Various
therapies have been reported to treat AKN with various results. Purpose: To
observe the efficacy of combination therapy for AKN. Case report: A 19-year-old
man presented with multiple pruritic papules, 0.1–0.3 cm in diameter on the
nape and occipital area. The histopathological examination revealed neutrophil,
eosinophil, and plasma cell infiltration in infundibulum, which was consistent
with AKN pathological patterns. Discussion: Combination therapy consisted of
0.025% tretinoin cream, 0.1% mometasone furoate cream, intralesional
triamcinolone acetonide 5 mg/ml, and doxycycline 2x100 mg. The improvement was
initially observed on 2nd week of follow up, as the lesions had reduced in size
and number, and the improvement became more significant on 4th week of follow
up. Conclusion: Combination therapy of topical tretinoin, topical and
intralesional steroid, and systemic doxycycline shows good result and can be
considered in the management of AKN.
Key words: acne keloidalis
nuchae, combination therapy
Penulis: Kartika Ruchiatan,
Erfina Rohana Sormin, Reti Hindritiani, Asmaja Soedarwoto, Hendra Gunawan
Kode Jurnal: jpkedokterandd170517
