RELATIONSHIP OF PERIURETHRAL FIBROTIC IN BPH PATIENT WITH LUTS AND URINARY RETENTION
Abstract: Analyzing the
differences between collagen thicknesses in periurethral region from
transurethral resection of the prostate (TURP) specimens of Benign Prostate
Hyperplasia (BPH) patients with lower urinary tract symptoms (LUTS) and of
those with urinary retention. Material & methods: This was an observation
analytic study on 30 patients who underwent TURP. Patients who met the
inclusion criteria were divided into 2 groups: BPH patients with LUTS and those
with urinary retention. Each group consisted of 15 people. The first TURP
specimen of proximal verumontanum resection were examined in anatomic pathology
using mass on strichrome staining as an examination of periurethral collagen thickness.
Collagen will be stained as blue. Periurethral collagen thickness was measured
from the basal membrane of transitional epithelium to fibromuscle tissue. Data
were then statistically analyzed using independent t-test. Results: The average
patient age was 66 ± 7 years old and there was no significant difference
between age and periurethral collagen thickness with p=0.175 (p>0.05). The
mean prostate volume was 47.19 ± 13.2 ml and there was no significant
difference between prostate volume and periurethral collagen thickness with
p=0.148 (p>0.05). Average periurethral collagen thickness in BPH patients
with urinary retention was 146.67 ± 39.80 micrometers and while in those with
LUTS was 205.33 ± 85.6 micrometers. There were no significant differences between
periurethral collagen thickness and the occurrence urinary retention with
retention of urine with p=0.063 (p>0.05). Conclusion: There were no
significant differences between periurethral collagen thickness patients in BPH
patients with LUTS and in those with urinary retention. This suggests that
periurethral collagen thickness is not associated with the occurrence of
urinary retention or LUTS in BPH patients.
Keywords: Periurethral
fibrosis; Collagen of periurethra; benign prostate hyperplasia
Author: Zamroni, Sunaryo
Hardjowijoto, Soetojo
Journal Code: jpkedokterangg170034
