Nasopharyngeal Non Hodgkin Lymphoma
Abstract: Non Hodgkin
lymphomas (NHL) are tumors originating from lymphoid tissue, mainly from lymph
nodes. These tumors may result from chromosomal translocation, infections,
environmental factors, immunodeficiency states, and chronic inflammation. In
general, the incidence of NHL is slightly higher in men than in women. The
incidence of NHL nasopharynx is rare. A high degree of suspicion is required to
avoid unnecessary radiologic and surgical procedures since NHL can be
mistakenly diagnosed as carcinoma. We reported a 16 year old male patient with
gradual epistaxis, hearing impairment, decreased body weight, and multiple
nodules in right forehead, right axilla, right colli posterior, and left waist.
The patient also suffered from inferior paraplegic extremities. The Head CT
scan result showed carcinoma nasopharynx. After biopsy of nodules was done, it
revealed differential diagnoses such as blastoma, Non Hodgkin lymphoma, and
small cell carcinoma. Immunohistochemistry result showed Leucocyte Common
Antigen (LCA) positive, and MRI thorax showed suspect of schwannoma. Based on
the data, chemotherapy with regiment CHOP (cyclophosphamide,
hydroxydaunorubicin, oncovin/vincristine, and prednisone) was given. The
prognosis of NHL Nasopharynx was better than nasopharyngeal squamous cell
carcinoma. The prognostic of NHL depends on the age, performance status,
staging, extranodal involvement, serum Lactate Dehydrogenase (LDH) and response
of therapy. The prognosis in our patient was poor.
Keywords: Mass, Non Hodgkin
Lymphoma, nasopharyngeal carcinoma, prognostic
Penulis: Shinta Oktya
Wardhani, Nanik Triana Kartikasari
Kode Jurnal: jpkedokterandd170363
