Hypertension as a Determining Factor in the Rupture of Intracranial Aneurysms, Diagnosed by 64-MDCT Angiography
Abstract: To determine a
correlation between risk factors and the rupture of intracranial aneurysms.
Methods: A cross-sectional study of 29 patients with a saccular intracranial
aneurysm was obtained using consecutive sampling and examination of 64-MDCT
angiography. Bivariate statistical analysis using Fisher's exact test was
arranged using cross-tabulation to determine the correlation between each risk
factor of age, sex, hypertension, and smoking with the occurrence of ruptured
intracranial aneurysms. Results: The highest incidence of ruptured intracranial
aneurysms were in patients aged <60 years (70%), male (75%), experienced
hypertension (85%), and were smokers (85.7%). Only the risk factor of
hypertension had a correlation with the occurrence of a ruptured intracranial
aneurysm (p < 0.05). The prevalence ratio of age and sex were 1.0 and 0.9,
whereas hypertension and smoking were 2.6 and 1.3. Conclusions: The risk factor
of hypertension leading to a ruptured intracranial aneurysm was 2.6 times
higher than non-hypertensive patients, and as such hypertension is a risk
factor associated with the occurrence of ruptured intracranial aneurysms
Keywords: intracranial
aneurysm; hypertension; 64-MDCT angiography
Author: Heni Fatmawati,
Antonius G Santoso
Journal Code: jpkedokterangg170245