Correlation between Neutrophil-Lymphocyte Ratio and Cardiac Autonomic Neuropathy in Diabetes Mellitus Type 2 Patients
ABSTRACT: To analyze the
correlation between cardiac autonomic neuropathy (CAN) and
neutrophil-lymphocyte ratio (NLR) in DM type 2 patients.
Methods: This was a cross-sectional study which was conducted at the
Internal Medicine Clinic of Dr. Hasan Sadikin General Hospital, Bandung and
Chronic Disease Management (CDM) Club in Garut District, West Java, Indonesia
from October to December 2015. Subjects were 57 DM type 2 patients who met the
inclusion criteria. Cardiac autonomic neuropathy examination and complete blood
count (CBC) were performed to discover the subjects’ neutrophil-lymphocyte
ratio.
Results: A strong correlation was found between CAN in DM type 2 patients
and NLR (r=0.679; p=0.000) based on Rank Spearman correlation test. The NLR to
CAN cut off point was 1.34.
Conclusions: NLR examination can be used as an indicator of CAN in DM
type 2 patients with NLR cut off point. There was a correlation between CAN and
DM type 2 diagnosis duration.
Keywords: Cardiac autonomic
neuropathy, diabetes mellitus type 2, Ewing test, neutrophil-lymphocyte ratio
Penulis: Cahyandari
Nurlaelatiningsih, Sunaryo Sastradimaja Barki Sastradimaja, Irma Ruslina Defi
Kode Jurnal: jpkedokterandd170221
