Complications as important predictors of disability in ischemic stroke
Abstract: Stroke is the main
cause of disability and death in many countries. The high incidence of
disability in stroke survivors requires special attention to determine various
predictive factors of disability. This study aimed to identify the various
predictive factors of disability in ischemic stroke.
Methods
This study was a cross sectional study on 4510 ischemic stroke patients.
Each patient’s data had been recorded in the electronic stroke registry of
Bethesda Hospital. Ischemic stroke diagnosis was confirmed by brain CT scan,
which was interpreted by a neurologist and a radiologist. Disability was
assessed using the modified Rankin scale. Predictors of disability were
assessed. Multiple logistic regression analysis was used to analyse the data.
Results
The subjects were predominantly males, >60 years of age, and suffered
stroke for the first time. The incidence of disability was 31.5% (1420/4510).
Multiple logistic regression analysis showed that the presence of complications
(OR: 6.43; 95% CI: 4.74-8.73; p<0.001), decreased level of consciousness
(OR: 4.82; 95% CI: 3.95-5.90; p <0.001), onset ³3 hours (OR: 1.93; 95% CI:
1.52-2.45; p<0.001), recurrent stroke (OR: 1.63; 95% CI: 1.39-1.90;
p<0.001), and age >60 years (OR: 1.55; 95% CI: 1.35-1.79; p<0.001)
were independent predictive factors of disability.
Conclusion
We demonstrated that a substantial proportion of patients with ischemic
stroke become disabled. And the presence of complications was the most
predictive factor of disability in ischemic stroke.
Keywords: Stroke, ischemic;
cohort study; predictive factors; disability
Author: Rizaldy Taslim Pinzon,
Rosa De Lima Renita Sanyasi
Journal Code: jpkedokterangg170056
