Burden of Pediatric Cancer Treatment: Results of Online Pediatric Cancer Registry Prototype 1 at A Third Referral Hospital in Indonesia
Abstract: Despite the
impressive progress of high-income countries, childhood cancer survival remains
low in low and middle-income countries. Cancer is yet to be considered as a
significant public health issue which has implicate only few pediatric cancer
registry has been well established. The study aimed to describe the burden of
pediatric cancer treatment in a third referral hospital in Indonesia through
pediatric cancer registry.
Methods: A-three-year retrospective analysis of 15 pediatric cancer
diagnosed in children aged under 14 years was conducted at Dr Hasan Sadikin
General Hospital, Bandung. Data were
extracted from Online Bandung Pediatric Cancer Registry Prototype 1 and analyzed
for age, gender, type of cancer. The outcomes were classified as treatment
abandonment, treatment refusal, interrupted treatment, death during treatment,
and completed treatment.
Results: Seven-hundred and seventy-three children, 452 males and 321
females, were diagnosed with 15 types of malignancies. Peak incidence for each malignancy was
different: at a young age was found in retinoblastoma and hepatoblastoma (mean;
3yo) while at adolescence in bone tumor and chronic myelocytic leukemia (9.1;
10 yo respectively). Distribution of the foremost malignancies recorded was:
acute lymphoblastic leukemia (44.5%), retinoblastoma (15.2%), and non-Hodgkin
lymphoma (8.9%). The cancer cure rate was very low (9.5%), treatment
abandonment was still high (41.7%) and most patients died (27.8%) in the course
of therapy either from advanced disease, infection, or late presentation.
Meanwhile, 167 patients still continued the interrupted treatment.
Conclusions: Cancer management is the burden for hospital, however the
general outcome is very poor.
Keywords: Cancer management,
developing countries, health care burden, pediatric cancer registry
Author: Nur Melani Sari,
Lelani Reniarti, Nur Suryawan, Susi Susanah, Kurnia Wahyudi
Journal Code: jpkedokterangg170164
