Bone Density Status and Vitamin D and Calcium Concentrations in Pregnant and Non-Pregnant Women
Abstract: The aim of this
study was to analyse differences in bone density and vitamin D and calcium
concentrations between pregnant and non-pregnant women. Methods: This was an
analytical, cross-sectional study of women aged 30 years or over, residing in
the Puskesmas Bangkalan district. The sample population was chosen at random
and included 10 pregnant women in their third trimester and 10 non-pregnant
women. This observational study consisted of an interview, a blood test, and a
24-hour recall. The concentration of serum vitamin D (25(OH)D) was measured by
Gas Chromatography and a Photometric Test measured the concentration of serum
calcium. Participant's bone density was measured by bone ultra sonometer. The
data was analysed using the Mann-Whitney test and assessed ultraviolet-B
exposure, bone density values, and consumption of vitamin D, calcium, energy,
and protein. The Student t-test was used
to analyse serum vitamin D and calcium concentrations. Results: There were no
differences between the groups' serum vitamin D concentrations (p = 0.946).
However, there were significant differences between the groups' serum calcium
concentrations (p = 0.047) and bone density values (p = 0.019). Conclusions: A
high prevalence of vitamin D deficiency (25(OH)D < 50 nmol/L) and
insufficiency (25(OH)D < 80 nmol/L) was observed in both groups. The mean
serum calcium concentrations and bone density values were lower in pregnant
subjects than non-pregnant subjects.
Keywords: bone density;
calcium; vitamin D
Author: Dini Setiarsih,
Bambang Wirjatmadi, Merryana Adriani
Journal Code: jpkedokterangg160317
