PROFIL OSTEOBLAS DAN OSTEOKLAS TULANG ALVEOLAR PADA MODEL TIKUS DIABETES TAHAP AWAL DENGAN APLIKASIGAYA ORTODONTI YANG BERBEDA
Abstract: Orthodontic tooth
movement is obtained through alveolar bone remodeling. Alveolar bone remodeling
includes resorption process that played by osteoclasts and bone formed process
that played by osteoblasts. Diabetes affects on orthodontic tooth movement. The
magnitude of orthodontic force that applied in the early stages of diabetic
conditions, would be a consideration of the alveolar bone remodeling process.
The purpose of this study was to determine osteoblast and osteoclast profile in
early stage of rat diabetic models with different orthodontic force
application. 24 Wistar rats were divided into three groups of controls andthree
groups of early stage of diabetic treatment with different orthodontic force
application (10, 20, and 30 gramforce/grf). The results showed an increased of
osteoclast numbers in early stage of diabetes and will be increased along with
the increased of orthodontic force. The results also showed a decreased of
osteoblast number in early stage of diabetes, but it would be increased along
with the increased of orthodontic force.
Penulis: Nuzulul Hikmah
Kode Jurnal: jpbiologidd150965
