PATOMEKANISME PENYAKIT GAGAL JANTUNG KONGESTIF
Abstract: Heart failure is a
clinical syndrome characterized by abnormalities in the structure or function
of the heart, resulting in inability of heart to pump blood to meet the
metabolic needs of the body tissue. Heart failure is characterized by clinical
manifestations such as circulation congestion, tightness, fatigue, and
weakness. Heart failure is a major problem in industrial and developing
Country. Currently, the incidence and prevalence of heart failure tends to
increase, it is also accompanied by an increase in mortality of heart failure
cases. In the United States, 1 million patients hospitalized due to heart
failure cases, which contribute to 50,000 deaths each year. While the number of
visits to the hospital due to heart failure estimated at 6.5 million. Heart
failure prognosis is generally poor despite the patients accepted adequate
therapy. From the data obtained, only about 35% of male patients and 50% female
patients who survived after the onset of acute heart failure. Generaly, the
data obtained high mortality are occurs in patients with grade IV (presence of
symptoms at rest) is about 30-70%, grade III (presence of symptoms with mild
activity) 10-20%, class II (presence of symptoms when the activity being 5-10
%). Higher mortality was found in older patients, men, patients with reduced
ejection fraction, and in patients with coronary disease. Once someone is
suffering from heart failure, then he shall bear the very high cost. In
America, the cost of issued for heart failure therapy between 15-40 trillion
US$. In this review, we will discuss about pathomechanism of heart failure. So
it is expected to be a reference to the diagnosis of patients with heart
failure, which is expected to be recognized early on that could ultimately
improve the quality of heart failure patient life, and reduce the number of
mortality due to heart failure.
Penulis: Lailia Nur Rachma
Kode Jurnal: jpbiologidd141087