DETEKSI DOPAMIN SECARA VOLTAMETRI MENGGUNAKAN ELEKTRODA PASTA KARBON TERMODIFIKASI ETER MAHKOTA (DIBENZO-18-CROWN-6)
Abstrak: The research about
the detection of dopamine by voltammetry method using crown ether modified
carbon paste electrode has been carried out. The aims of this research are to
investigate the influence of pH and the composition of modifier to the
sensitivity and limit of detection for dopamine analysis. The measurement was
conducted by differential pulse voltammetry method.The optimum of pH and
modifier (crown ether) composition in the detection of dopamine are 4,0 and
0.8%, respectively. The linear concentration range is obtained from 10 to 200
μM, linear regression equation y = 4,968 + 0,068x with R2 = 0,9988 and limit of
detection 6,865 x 10-6 M. The modified carbon paste electrode has relative
standard deviation smaller than Horwitz’s (1,28%<5,66%), therefore this
electrode has a good reproducibility. The recovery using crown ether-modified
carbon paste electrode is 99,0% showing a good accuration. The measurement of
commercial samples contain dopamine HCl (Giulini and Proinfark injection) is
87,0% and 91,5% compared with the composition on the label
Penulis: Irdawati, Manuntun
Manurung, Kadek Adi Septiawan
Kode Jurnal: jpkimiadd150405
