AKTIVITAS ANTIHIPERGLIKEMIK DARI EKSTRAK ETANOL DAN n-HEKSANA DAUN KEMBANG BULAN [Tithonia diversifolia A.Gray] PADA TIKUS PUTIH JANTAN
Abstrak: Phytochemical test
and antihyperglicemic activity from ethanol extract dan n-hexane extract from
kembang bulan (Tithonia diversifolia A.Gray) leaf has been carried out. Based
on the test result of phytochemistry of secondary metabolites compounds from kembang
bulan (Tithonia diversifolia A.Gray) leaf showed that ethanol extract fraction
containing flavonoid, fenolik, alkaloid and saponin. Whereas at n-hexane
extract fraction containing alkaloid, saponin and steroid. Antihyperglicemic
activity test using the method of glucose tolerance where a white male rats got
induced by sucrose. Measurement of blood sugar levels using glucometer and
glucose test strip. From this test shows that the most active fractions to
reduce blood sugar levels was ethanol extract with a dose of 77 mg/kg BB with
percentage of blood sugar levels reduction in the amount of 54.15 % it was
close with reduction percentage from acarbose as positive control in the amount
of 55.57 %.
Kata Kunci: kembang bulan
(Tithonia diversifolia A.Gray) leaf, phytochemistry test, antihyperglicemic
activity, glucose tolerance, glucometer and glucose test strip
Penulis: Ary Rizki Darmawi,
Chairul Saleh, Rudi Kartika
Kode Jurnal: jpkimiadd150401
