THE DIFFERENCE OF NATURAL KILLER CELL ACTIVITIES OF THE PEOPLE LIVE IN THE AIRCRAFT NOISE AREA OF ADI SOEMARMO AIRPORT BOYOLALI, SURAKARTA, INDONESIA
ABSTRACT: Exposure to noises
contributes to a health risk. There is sufficient scientific evidence that noise
exposure could induce hearing impairment, hypertension and ischemic heart
disease, annoyance, sleep disturbances, and decreased school performance. Other
evidence as changes in the immune system and birth defects is limited. The aims
of this study is to find out the difference of Natural Killer (NK) cell
activities of the people live in the aircraft noise area of Adi Sumarmo
Airport, Boyolali, Surakarta, Indonesia. The research design was an analytical
with a cross sectional approach, taking location at the Dibal and Gagak Sipat
Villages, Ngemplak Sub district, Boyolali District. The study was conducted
from June 2008 to June 2009. The number of subjects involved was 39. They were
divided into 3 groups. Group 1 was exposed to 52.17 dB of noise level (13
respondents). Group 2 was exposed to 71.79 dB of noise level (13 respondents),
and Group 3was exposed to 92.29 dB of noise level (13 respondents). The
cytotoxicities of NK cells was measured by flowcytometric and using a
non-radioactive method. The samples were taken using a simple random sampling.
The data were analyzed by Anova followed by Post Hoc Test using LSD test
completed with Homogenous Subsets. The results showed that the activity of NK
cells of Group 1, 2 and 3 were 12.50 + 3.25%,17.20 3.06%, and 22.33 6.30 %,
respectively. The Anova test showed that there was a significant difference of
NK cell activities, in the groups of respondents (p =0.000). In conclusion,
there was a significant difference of the NK cell activities of the people live
in the aircraft noise area of Adi Sumarmo Airport, Boyolali, Surakarta,
Indonesia.
Author: Hartono
Journal Code: jpkedokterangg110223
