Pengaruh Ekstrak Metanol, Fraksi N-Heksana, dan Fraksi Metanol Biji Pepaya (Carica papaya L.) terhadap Kadar Testosteron dan Bobot Organ Reproduksi Tikus Jantan
Abstract: Papaya seeds (Carica
papaya L.) was known have antifertility activity. Testosterone hormone and reproduction
organs weight are influence antifertility activity. This study was conducted to
compare the effect of the methanolic extract, fraction of n-hexane, and
fraction of methanol papaya seeds ( dose 100 mg/kg BW ) with testosterone level
and reproduction organs weight parameters of male rats. Measurement of
testosterone level by ELISA method. The observation found that the three
treatment didn’t decrease reproduction organs weight but decrease testosterone
level compared to negative control group. Among the three treatments,
metyhanolic extract and methanolic fraction decreased testosterone level.
Extract and fraction of methanol alleged alkaloid content of which is known to
inhibit development and count of spermatogenic cell.
Penulis: Dwi Puspita Sari,
Siti Muslichah, Wiratmo Wiratmo
Kode Jurnal: jpkesmasdd140363
