Endoscopical appearances of nonsteroidal anti inflammatory drug (NSAID)- enteropathy
Abstract: Non Steroidal Anti
Inflammatory Drugs (NSAID) have been associated with a sudden and sustained
rise in the incidence of gastrointestinal ulcer complications. The aim of the
study was to reveal the endoscopical abnormalities found in the duodenum &
proximal jejunum due to NSAID. Thirty eight patients taking NSAID for their
arthritis or rheumatism were included in this study. Gastro-duodeno-jejunoscopy
was done with Olympus PCF-10. The endoscopical appearances of NSAID entero
gastropathy were evaluated with a scoring system. The NSAID-entero-gastropathy
appearances were endoscopically seen as hyperemia, erosion and ulcer. From all
patient recruited, 7.9% complaint of diarrhea and 71.1% complaint of dyspepsia.
Endoscopically, in the duodenal bulb we found 79% cases of hyperemia, 39.5%
cases of erosion and 7.9% cases of ulcer. In the second part (descending part)
of the duodenum we found 28.9% cases of hyperemia, 15.8% cases of erosion and
2.6% case of ulcer. In the jejunum, we found 7.9% cases of hyperemia, 2.6% case
of erosion and no ulcer. It is concluded that the most frequent abnormal
endoscopical appearances in NSAID- enteropathy was hyperemia. The most frequent
site of NSAID-enteropathy abnormal findings was in the duodenal bulb.
Author: Marcellus Simadibrata,
G. N.J. Tytgat, L. A. Lesman, Daldiyono Daldiyono, Iwan Ariawan
Journal Code: jpkedokterangg050140
