EFEKTIVITAS PEMBERIAN KOMBINASI MINERAL ZINC DAN HERBAL SEBAGAI IMUNOMODULATOR
ABSTRACT: Suplemen as
imunomodulator used to increase immune response, to prevent disease. Herb and
Zinc (Zn) can function as imunostimulan. The aim of this experiment was (1) to
studythe effect of Zn mineral and herb combination influence the healthy
condition, performance and immunity responses, 2) to have blood biochemistry
and organ function in broiler who given zinc mineral and herb combination, 3)
to know the effectivity of herb and Zn to be treated by Colibacillosis
condition One hundred broiler were used in this research, divided by 5 groups:
RO (control), R1 (RO + 2.5% garlic powder+ 1.5% turmeric powder), R2 (R0+2.5%
garlic powder+ZnO 120ppm), R3 (R0+1.5% turmeric powder+ZnO 120ppm), R4 (R0+2.5%
garlic powder +1,5% turmeric powder and ZnO 120ppm). The parameters in this
research are the erythrocyte count, hemoglobin, and pack cell volume and total
leucocyte. Blood biochemistry are investigate protein total, albumin, alanine
aminotransferase (AL T), aspartat aminotransferase (AST), creatinin and ureum.
The research showed that the erythrocyte count, hemoglobin, and pack cell and
blood biochemistry in normal value, that explain safety for organ function and
health group showing health status and performance is good, tested in ability
to attack Colibasilosis. The result of research show and hematologi in normal,
The age of chicken was 3 weeks, all of groups were treated by innoculum of
Eschericia coli (E. col!) bacteria with 108 CFU.mr1 doses per-ons. The
parameter was based on performance, health condition, and immunity responses.
The activity and the capacity of phagositosis for assessments immunity respons,
the result showed to decerease the performance and healthy condition at the
first week infection, then converse to improve at the second week. The amount of
leucocyt cell, especially heterophyl cell was increased at 1 week after
infection as being indicated by the appearance of innoculum E. coli bacteria.
The amount of leaucocyt cell was decreased directly after 2 weeks post
infection at the group that was fed by turmeric-Zn (P1) and gave antibiotic
(K+) drug. This condition showed that the body defence fastly to eliminate the
infected agent which was supported by increasing phagocyitosis capacity
(327±111 bacteria) and phagocyitosis activity 97%±10%, was compared with the
control group (without drug) activity value 85±15% and phagocytosis capacity
(176±118 bacteria). Feeding by turmeric-Zn combination showed better result
which was compared to Garlic-Zn combination and the ability to increase healthy
condition, performance and immunuity responses.
Penulis: Sus Derthi Widhyari,
Ietje Wientarsih, Harry Soehartono, I Putu Kompiang, Wiwin Winarsih
Kode Jurnal: jppertaniandd090082
