Hubungan Kuantitatif Struktur Elektronik dan Aktivitas Inhibisi Senyawa Kurkumin pada Reaksi Etoksiresorufin O-Dealkilasi (EROD)
ABSTRACT: Electronic structure
and inhibition activity relationship study of curcumin analogs has been
established for 29 curcumin analogs on Ethoxyresorufin O-Dealkylation (EROD) reaction
using atomic net charge descriptor based on AM1 semiempirical calculations. The
QSAR (Quantitative Structure and Activities Relationships) equation model was
determined by statistical parameter from multiple regression analysis and
leave-one-out cross validation method. The best QSAR equation was described:
Penulis: Harno Dwi Pranowo,
Iqmal Tahir, Ajidarma Widiatmoko
Kode Jurnal: jpkimiadd070086
