UJI FETOTOKSISITAS EKSTRAK DAUN KEMANGI (Ocimum Sanctum L.) PADA MENCIT PUTIH
ABSTRACT: The fetotoxicity
effect of methanolic extract of the leaf of kemangi (Ocimum Sanctum L.) on mice had been
studied. The extract was given orally at various doses of 50, 100, and 200 mg/kg
BW at 6th until 15th day of
pregnancy. On the 18th day of pregnancy
laparactomy was perpormed on half
number of fetuses
from each litter.
Mice on doses
of 500 mg/kg
BW showed abortion. Macroscopic
observation on the
fetuses showed some
anomalis of body weight compared to control but there was
no malformation occured at all doses.
Penulis: Almahdy A dan Marina
Yandri
Kode Jurnal: jpfarmasidd100035
