KAJIAN TOKSISITAS EKSTRAK TUMBUHAN Talinum triangulare (Jacq) Willd.
ABSTRACT: Toxicity studies
have been conducted from plant extracts of Talinum triangulare (Jacq) Willd. on male
white mice. Toxic
effects were observed
in the form
of liver dysfunction
and renal dysfunction of
experimental animals that
were given orally
by the variation
extract dose of 150,
300 and 600
mg / kg
once daily for
15, 30 and
45 days. As
a control group
used male white mice which were
given only 2.5% Tween 80. Parameters to be measured are the activity of SGPT
and SGOT, creatinine
clearance, renal function
and percentage ratio
of kidney weight. From
the results of
studies it appears
that administration of
plant extract Talinum triangulare (Jacq)
Willd. with a
given dose affects
liver function and
kidney function were significantly (P <0.05).
Penulis: Erlina Rustam,
Machdawaty Masri, Helmi Arifin
Kode Jurnal: jpfarmasidd110068
