Green Antibiotic Daun Sirih (Piper betle l.) Sebagai Pengganti Antibiotik Komersial untuk Penanganan Mastitis
ABSTRACT: The present study
was carried out to investigate the possible antibacterial activity of betel
leaf on the amount and microscopic appearance of mastitis-causing bacteria. The
randomized block design with 5 treatment groups were : K group (mastitis milk
only as negative control), Ab group (mastitis milk + antibiotic
penicillin-dihydrostreptomycin as positive control), S1 group (mastitis milk + 1,25 ml betel leaf
water extract), S2 group (mastitis milk+ 2,5 ml betel leaf water extract), and
S3 group (mastitis milk + 5 ml betel leaf water extract). The result showed
that the amount of bacteria in the betel leaves groups (S1, S2, and S3 groups)
were lower (P< 0,05) than that of the control group (K group). Nonetheless
the different concentration of betel leaf water extract in the S1, S2 and S3
groups did not affect to the amount of bacteria (P> 0,05). Moreover, this
research showed that betel leaf water extract had the same effectiveness with
commercial antibiotic penicillin-dihydrostreptomycin to inhibit the growth of
bacteria as indicated by the same amount of bacteria (P>0,05) among the
betel leaf groups (S1, S2, and S3 groups) and the Ab group. Gram-positive and
negative bacteria were seen in the K group. However, only Gram-negative bacteria
were visible in the betel leaf groups (S1, S2, and S3 groups) and in the Ab
groups, indicating that betel leaf had the same effectiveness as
penicillin-dihydrostreptomycin to inhibit the growth of Gram-positive bacteria.
Penulis: Gabby
Lutviandhitarani, Dian Wahyu Harjanti, Fajar Wahyono
Kode Jurnal: jppeternakandd150020
