FORMULASI DAN UJI EFEKTIVITAS SEDIAAN SIRUP EKSTRAK ETANOL BIJI PEPAYA (CARICA PAPAYA L.) SEBAGAI ANTELMINTIK TERHADAP CACING ASCARIDIA GALLISECARA IN VITRO
ABSTRACT: Papaya kernel has
known as traditional medicine which is effective as an antelmintic. Papaya karnel extract contains
from carpain compound which is effective as an antelmintic. This research is
intent to formulate, to testthe quality and the efectivity of papaya kernel
etanol extract syrup. As an antelmintic towards Ascaridiagalliworm. The
antelmintic activity towards Ascaridiagalli worms which were being submerged
into 2 control groups, they are positive control (pirantelpamoat) and negative
control (syrup simplex) and papaya kernel etanolestract syrup were made in
threeactiveessense concentration variation they are 10%, 20%, 30%. The quality test result of papaya kernel etanol
extract syrup are: it has a good homogeneity, has a special papaya kernel
smell, has bitter taste, yellow colored, and has pH 5-6,5. The efectivity test
of papaya kernel etanol extract syrup towards Ascaridiagalliworms, in
concertration 10% and 20% has antelmintic effects but the highest capability is
in concentration 30%.
Penulis: MeykePattianakotta,
Fatimawali, Hamidah Sri Supriati
Kode Jurnal: jpfarmasidd140103
