ANALISA DRUG RELATED PROBLEMS PADA PASIEN DISLIPIDEMIA DI BANGSAL RAWAT INAP DAN RAWAT JALAN PENYAKIT DALAM RSUP DR. M. DJAMIL PADANG
ABSTRACT: Dyslipidemia is
an abnormality of
lipid metabolism, which
is characterized by elevated
or reduced plasma
lipid fractions. Dyslipidemia
is a major
risk factor of cardiovascular disease.
An Improve of
lipid profile may
reduce the risk
of cardiovascular disease. This
research was conducted
to determine the
Drug Related Problems
(DRPs) occured in patients with dyslipidemia.
This research was a prospective observational study using descriptive
cross sectional pproach, performed on
dyslipidemia patients with or without comorbidities in outpatient and inpatient of Internal Medicine DR. M.
Djamil Padang from March to May 2011.
Evaluation of the data was carried out descriptively.
Results showed that
type of DRPs
occurred from 11
dyslipidemia patients with
or without comorbidities on inpatient of Internal Medicine were
drug interactions in 4 patients, adverse drug reactions in 2
patients, noncompliance in 2 patients, dosage too high in 1 patient, inappropriate drug administration interval
in 1 patient while other
components of DRPs
hadno problem. In
the outpatient of
Internal Medicine, DRPs
occured at 98
patients of dyslipidemia with
or without accompanying
diseases were drug
interactions in 26
patients, patient noncompliance in
22 patients, adverse drug reactions in
13 patients, dosage too low in 5
patients, drug therapy
without medical indications
in 4 patients,
inappropriate drug administration interval
in 3 patients
while other components
DRPs had no
problem. Drug interactions
consisted of pharmacokinetic and
pharmacodynamic
interactions. In practice, those can
be accommodates by
separating their administration and
monitoring of drug interaction. Meanwhile, toxic drug
interactions were not found.
Penulis: Yuliana Arsil, Helmi
Arifin, Deswinar Darwin, Raveinal
Kode Jurnal: jpfarmasidd110097
