The Profile of Tear Mucin Layer and Impression Cytology in Pterygium Patients
ABSTRACT: The purpose of this
study is to assess the profile of tear mucin layer and impression cytology in
eyes with and without pterygium. A cross sectional study was conducted in Dr.
Wahidin Sudirohusodo Hospital and BKMM Makassar. Patients with unilateral primary
pterygium who visited both centers during the period from 1 January to 31
August 2009 were included. There were 34 subjects (68 eyes) with unilateral
primary pterygium fulfilled the criteria. Tear mucin layers were examined by
Break Up Time (BUT) test, Tear Ferning Test (TFT) and impression cytology test
of the bulbar conjunctiva on both eyes of the subjects with pterygium as well
as fellow eye (without pterygium). The result of this study showed that average
BUT value in eyes with pterygium was 8.44 seconds and in eyes without pterygium
was 13.84 seconds. TFT degree in eyes with pterygium was grade 3 and 4 while
eyes without pterygium was grade 1 and 2. Impression cytology in eyes with
pterygium was grade 2–3, while eyes without pterygium was grade 0–1. These
differences were statistically significant (p < 0.05). No significant
correlation was found between patient’s condition (age, sex and occupation) and
tear mucin layer, impression cytology. Most of cases with medial pterygium,
third stage and intermediate (T2)/fleshy (T3) pterygium type had abnormalities
in mucin and impression cytology. It is concluded that there are significant
abnormalities of tear mucin layer and impression cytology in eyes with
pterygium.
Penulis: Djajakusli Shintya,
Rukiah Syawal, Junaedi Sirajuddin, Noor Syamsu
Kode Jurnal: jpkedokterandd100026
