Perbandingan Hasil Positif Uji BCG dan Uji Tuberkulin sebagai Uji Tapis pada Anak dengan Tuberkulosis
Abstract: Until now
tuberculosis (TB) is still a world health problem, especially in the third
world countries like Indonesia. World health Organization (WHO) reported in
1995 there were 3 millions people died caused by TB. Prevalence of lung TB with positive acid fast bacili (AFB) in
Indonesia is still high, about 0.3%, it means that there were 3 persons suffering
of TB every 1000 people. It's needed to improve the quality of lung TB disease
elimination program. But, the problem that some of the cases of tuberculosis
with positive AFB finding is low. May be
it caused that the technique of AFB examination is dificult, especially in
infant and young children. tuberculin test have been used widely for a long
periode, but it reaction less sensitive (to be negative) for a moment time in
anergy state. Recently, some centre uses BCG for diagnosing TB, but fur ther
research is still needed (to prove more high proportion of positive result and superiority of BCG test). This
research uses Clinical Disagreement to measurekappa and chi square (Fisher's
Exact test) to mesurep. The sample size
were 100 respondents, boys and girls beetwen 4 months to 12 years old, who
visited to General Pediatric Clinic and Pulmonology Clinic Dr Kariadi Hospital.
T o diagnosing TB, modified 1994 Starke Criteria is used. Tuberculin and BCG test was tested at the
same time and evaluated after 72 hours (for tuberculin and BCG) and at 7th day
(for BCG). The proportion of these tests were compared by cross tabulation. The respondents that suffering of tuberculosis
were treated with 2HRZ 4HR regiment and reevaluated clinical, laboratoric and
radiologic findings. The proportion of
positive result of BCG test is higher (97%) than positive result of tuberculin
test (24%), but not significant. Proportion of negative result of tuberculin
test is higher (78%) than BCG test (3.3%), but not significant. Distribution of
positive result of BCG test has the same proportion in groups of age and
nutrition state. The proportion of positive result of BCG test is higher than
tuberculin test, but not significant.
Penulis: Mohammad Wildan
Kode Jurnal: jpkedokterandd090043
