Pengaruh Pemberian Ekstrak Air Daun Jati Belanda (Guazuma Ulmifolia Lamk.) terhadap Kadar Lipid Darah pada Tikus Jantan
Abstract: Jati belanda
(Guazumaulmifolia Lamk) has traditionally been used as a slimming agent. This
study attempted to determine the effect of water extract of jati belanda on the
blood lipid concentration of Wistar rats
induced - hyperlipidemia. These rats were divided into four groups, each
consisting of five rats. Three of these groups were subsequently induced by (1)
jati belanda extract at a dose of 25 mg/kg body weight, (2) jati belanda
extract at a dose of 50 mg/kg body weight, and (3) simvastatin. The fourth was
the control group. The extract as well as the simvastatin was given orally for
14 days whereas the control group received vehicle. Blood lipid concentration
was determined on day 7 and day 14. The result of this study was analyzed
statistically using SPSS program. The result showed that the group induced with
water extract of jati belanda at a dose of 50 mg/kg body weight had a
significantly lower level of total cholesterol and LDL cholesterol than the
control group.
Penulis: Elin Yulinah
Sukandar, Elfahmi, Nurdewi
Kode Jurnal: jpkedokterandd090079
