Identifikasi Protein Hemaglutinin Pili Proteus Mirabilis P 355
Abstract: Urinary tract
infection represent one of nosocomial infection in hospital. One of agent
nosocomial urinary tract infection is Proteus mirabilis and common occurs on
patient with urinary catheter. Urinary tract infection in with caused by
Proteus mirabilis was persistent, very difficult to eradicated. Futher more it
caused some complication such as cystitis, acute and chronic pyelonephritis,
kidney bladder stone, bacteremia and sepsis. This bacterium has same virulence
factors. Fimbriae is one of it.
The purpose of this research is to identify hemaglutinin protein of Proteus mirabilis P355 pili. In this study
protein of pili was isolated, and than continued with the hemaglutination test.
The result of this study shown that
hemaglutination test was positive in protein pili with 35,2 kDa, 27,9
kDa, 24 kDa and 22 kDa molecular weight. The highest titer of hemaglutination
(1/512) wa found on protein pili with 35,2 kDa molecular weight.
Penulis: Diana Chusna Mufida
Kode Jurnal: jpkedokterandd080015