Gambaran Fungsi Hormon Tiroid Pada Penderita DM Tipe 2 Rawat Jalan
Abstract: In
previous studies reported
that impaired of
thyroid function in
patients with type 2
diabetes showed different
results. This study
aims to know
the description of
the thyroid hormone function in type 2 diabetes mellitus outpatient. Methods: A
cross sectional study
was conducted from
September 2009 -
March 2010 in
H. Adam Malik General
Hospital. The subjects
were all outpatients
at the clinic
of Endocrine and
Metabolic who met the
criteria participated in this
study. All samples were examined of TSHs, FT4,
adrandom blood glucose, Total cholesterol, HDL cholesterol, and LDL
cholesterol.
Results: There were
40 patients with
type 2 diabetes
who had participated
in study with
19 men (47.5%), and 21 women
(52.5%) with mean age of 58.3 years. We found thyroid dysfunction is 10% or 4
people and in details, 2 people (5%) of subclinical hypothyroidism and 2 people
(5%) of subclinical hyperthyroidism.
There were significant
differences in average
concentrations of three
TSHs groups (p1 =
0.0010, p2 =
0.012, p3 =
0.001), whereas FT4
significantly different in
eutiroid group and subclinical hyperthyroidism (p2
= 0.001) and
subclinical hypothyroidism group
and subclinical hyperthyroidism
(p3 = 0.001). TSHs levels correlated positively and statistically significant
with total cholesterol (r = 0.989, p = 0,011)
Conclusions: Overview of
thyroid hormone function
in 40 patients
with type 2
diabetes mellitus indicates 10%
of dysfunction with more women than men,
and ages who have been affected is over 60 years.(JKS 2010; 1: 1-8)
Penulis: Mardianto, Suherdy,
Dharma Lindarto
Kode Jurnal: jpkedokterandd100004
